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Individuals with certain genetic variants may be more susceptible to environmental factors such as stress, infections, or iodine exposure, which can initiate or exacerbate the autoimmune process
Park HJ et al
42 AKT directly and indirectlyby the activation of mTOR, which promotes the stabilization of the transcription factor hypoxia-inducible factor-1stimulates the expression of glucose transporters and key glycolytic enzymes (Figure 3)
PnAc enabled the demonstration of an exacerbated lipid peroxidation in the mitochondrial membranes of CFBE41o-cells compared to 16HBE14o-cells, thereby adding to the cumulative evidence of increased oxidative damage at the mitochondrial level in CF (Atlante et al., 2016)
doi: 10.3810/pgm.2012.11.2615, 22
Saraiva, C
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