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MPs taken orally into the GI tract are not fully absorbed by the intestinal epithelium and the unabsorbed portion is transported across the intestinal vascular barrier to all parts of the body, leading to systemic inflammation
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This is the class of medications that has truly revolutionized modern weight management
When calorie intake drops that sharply, the body does not exclusively burn stored fat
That is where glycine enters the equation
Ensuring adequate hydration is therefore an important consideration with GLP-1 RA treatment, as is recommended by the label, particularly for people with renal impairment, as dehydration is known to be associated with renal dysfunction [98]
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