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The mean changes from baseline to week 26 were -1.4 kg, -2.3 kg and -3.7 kg in the placebo, RYBELSUS 7 mg and RYBELSUS 14 mg arms, respectively

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The bigger weight loss with tirzepatide likely happens because it works on two hormone systems instead of one

And if, like so many of our clients, youre tempted by this incredible weight-loss solution, youll undoubtedly have questions as well

Exendin-4 has been shown to cross the blood-brain barrier (BBB) at high doses in mice [20], and exenatide demonstrates the fastest rates of brain influx compared to GLP-1 receptor agonists lixisenatide, liraglutide, and semaglutide [21]