DPP-4 inhibitors increase the endogenous GLP-1 concentrations ~2-3-fold, GLP-1 receptor agonists lead to 8-10-fold concentrations
Every process in your body that keeps you moving, thinking, and breathing runs, at the most basic level, on the flow of electrons whether that's giving, taking, or sharing electrons
Kidney Int 66:12121220
This allows for personalized dosing, different delivery methods, and the ability to combine multiple medications into a single formulation
Inflammasomes Inflammasomes are multiprotein complexes that were first proposed in 2002
Given the limited availability of pediatric data for dual and triple agonists, evidence from adult clinical trials was included where relevant to provide mechanistic insights and contextual understanding