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On status: tesamorelin (brand Egrifta) was first FDA-approved in November 2010

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Its purpose is to streamline protein purification processes for research and therapeutic applications

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In preclinical animal models, administration of IL-1 inhibitors, including IL-1 receptor antagonists (IL-1RA) or anti-IL-1 antibodies, has been shown to mitigate liver inflammation, steatosis, and fibrosis [134]

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