Both GLP-1 analogs and exendin 939 were found to reduce CAP-induced inward currents and calcium influx through the TRPV1 channel
Possible complications related to GLP-1 use under anesthesia include: Aspiration due to delayed gastric emptying Hemodynamic instability: pronounced hypotension or bradycardia Altered response to opioids and sedatives, requiring dose changes Perioperative hypoglycemia from additive glucose-lowering effects Nausea and vomiting increasing postoperative airway risk Delayed recovery of bowel function, affecting discharge timing Interference with regional anesthesia sympathetic block assessment Post-Surgery Restart Post-surgery restart of GLP-1 receptor agonists should be done with clear criteria and close coordination to avoid complications and maintain therapeutic goals
Fibrosis Improvement : Emerging evidence suggests that GLP-1 medications may help slow or even reverse the progression of liver fibrosis, a condition in which excessive scar tissue forms in the liver
When used as directed, its safe, effective, and non-stimulating
While branded GLP-1s were in shortage, many compounding pharmacies offered lower-cost alternatives that proved to be very popular, with an estimated 2-4 million Americans prescribed a compounded GLP-1
It is a once-daily subcutaneous injectable prescription medicine
