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To determine dose level and dose frequency of central administration of mGIPR-Ab, pharmacokinetic profile of ( a ) brain and ( b ) plasma exposure was assessed at 4, 24, 72, 120, and 168 h following a single ICV injection of 15 g/L/mouse dose of mGIPR-Ab
Buckley ST et al
Physicians must have systems in place for tracking patients over time monitoring for adverse effects, assessing muscle mass changes, evaluating dietary habits, and managing the rebound weight gain that frequently occurs when patients stop the drug
17 Dulaglutide EMA product information (2023)
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