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However, similar to what we observed for strep-MBP-GRXC2, strep-MBP-HsGRX1 became oxidized already upon addition of GSH, resulting in two main protein species which persisted over a wide range of GSH/GSSG ratios (Fig

CR also altered DNMT3a levels in the hippocampus of mice and improved brain function in mice during aging ( etc

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Here is where the distinction between preclinical and clinical data becomes critical

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