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The commonly reported crash after stopping is not withdrawal, but a return to baseline physiology

4.3 Oxygen transport agents Agents like trans-sodium crocetinate (TSC) (C 20 H 22 Na 2 O 4 ), derived from crocetin (C 20 H 24 O 4 ), interact with water molecules to form a densely packed matrix that enhances oxygen diffusion into hypoxic tissue sites (156)

A second portion of the endometrial biopsy was placed in RNAlater (Sigma-Aldrich Canada, Oakville, ON, Canada), kept at 4 C overnight, and then stored at 80 C until processed for nucleic acid extraction

A sterile syringe for measuring and transferring the water

The analysis parameters were set according to Smart et al

Aziz I, Palsson OS, Whitehead WE, Sperber AD, Simrn M, Trnblom H