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The AAFPs evidence-based clinical review states directly: Oral administration of high-dose vitamin B12 (1 to 2 mg daily) is as effective as intramuscular administration for correcting anemia and neurologic symptoms in patients with B12 deficiency (Langan RC, Goodbred AJ, American Family Physician, 2017)
1e, 1g1i, 2c2d and 4b4d are provided as a Source Data File
Chi, L., Ke, Y., Luo, C., Gozal, D
doi: 10.1056/NEJMoa1710922 279 MonariC.CasadevallA.RetiniC.BaldelliF.BistoniF.VecchiarelliA.et al
503B outsourcing facilities: operate under FDA registration, produce larger lots that clinics can stock for office use, and must follow current good manufacturing practice standards
It is a prescribed compounded medication that needs a provider intake, dose titration, and follow-up, exactly like any other clinical prescription
