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CBS, a heme protein, is active in the oxidized form, whereas methionine synthase is inactivated by oxidation and requires reductive methylation for reactivity (Chen and Banerjee, 1998

Watch for the characteristic blue color developing as copper-peptide complex goes into solution

This means its effects are intriguing but still require more scientific validation before being fully accepted in medical practice

The hemoglobin is metabolized to bilirubin (causing jaundice at high concentrations)

This process is known as adaptive homeostasis or allostasis (Sies et al., 2022)

10.1074/jbc.M410818200 31 PiJ.BaiY.ZhangQ.WongV.FloeringL