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Pharmacological inhibition of ferroptosis suppresses renal fibrosis induced by UUO To determine whether target-mediated inhibition of ferroptosis can effectively delay renal fibrosis, we examined the effects of Fer-1, a specific ferroptosis inhibitor that inhibits lipid peroxidation synthesis by reducing oxygen radical production (Fig

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In contrast, abundant evidence demonstrates that enhancing Nrf2 signaling is potently neuroprotective in models of neurodegeneration, although the exact mechanism by which this is achieved is unclear

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Biol Chem 390, 191214.CrossRefGoogle ScholarPubMed Weschawalit, S, Thongthip, S, Phutrakool, P, et al

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Sin embargo, en los ltimos meses, las autoridades reguladoras de medicamentos tambin han documentado efectos secundarios raros, ocasionalmente graves, asociados con el uso de estos agentes en el tratamiento de la diabetes de los que los mdicos no necesariamente estaban al tanto

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