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One study showed that, when applied to the skin, MSM significantly improved redness, itching, inflammation, hydration and skin color in people with rosacea ( Summary MSM may improve skin health by strengthening keratin and reducing inflammation

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And the first big paper that talked about this was actually in Nature Medicine in 2003, and it was originally, I think I should credit Nigel Greig

National and international guidelines consistently position lifestyle modification as the first-line intervention for obesity treatment

Retrieved February 25, 2020.