(PubMed) Cheatham CL, Goldman BD, Fischer LM, da Costa KA, Reznick JS, Zeisel SH
In addition to iron-catalyzed free radical chain reactions, lipoxygenase (LOXs) can directly oxidize PUFAs and lipid-containing PUFAs in cell membranes, which are considered to have an essential role in ferroptosis [75, 80]
It is structurally designed to interact with metabolic enzyme pathways and has become a subject of interest in metabolic and mitochondrial research fields
for example, there's some group in Africa somewhere that that's all they eat is cabbage, and there's a goitrogen in cabbage
Notably, effects were achieved via multiple routes of application including intragastric and local, suggesting broad applicability across experimental delivery methods
There were no significant differences between GSSG and GSH groups