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Chemically labile linkers, such as acid-sensitive hydrazones and silyl ethers, respond to environmental changes like pH or redox conditions

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Autophagy exhibits selectivity in degrading certain cargoes such as mitochondria (mitophagy) endoplasmic reticulum (reticulophagy), intracellular microbes (xenophagy), lipid droplets (lipophagy), peroxisomes (pexophagy) and glycogen (glyophagy) or non-selective to degrade random parts of the cytoplasm (144)

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Tretinoin is a regulated prescription drug in most countries, including the United States (FDA) and across the EU

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