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Symptoms can include rash, itching, or, in severe cases, anaphylaxis

The body must use a demanding methylation reaction process to separate the B12 out of this synthetic form so that it can be converted to a usable, absorbable form

But if the deficiency is caused by an irreversible inability to absorb the vitamin, a lifelong treatment with pharmacological doses of B12 is needed

Both also play a role in immune system health

Vitamin B12 is essential during pregnancy and breastfeeding for fetal neurological development and maternal health

Managing gastrointestinal side effects, particularly nausea, requires a multifaceted approach that may include both behavioral modifications and potential medical interventions