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This dual-receptor profile makes it especially relevant in research focused on obesity, glucose homeostasis, insulin signalling, energy balance and next-generation metabolic therapeutics

Some experienced radiologists feel that contrast may help to reveal melanosis in this setting (personal communication, AJ Barkovich, Neuroradiology- UCSF )

Weight is one metric, but it is not the only one

However, significant peeling or irritation is a sign of over-exfoliation

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For some individuals, metabolic or bariatric surgery, such as gastric sleeve, gastric bypass or endoscopic sleeve procedures, may be appropriate