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While on tirzepatide, magnesium can serve multiple purposes
Combining the two without aggressively hydrating can lead to severe headaches, dizziness, and fatigue the next day
The glucagon receptor component is hypothesised to increase energy expenditure and promote fat breakdown (lipolysis), potentially offering additional weight loss benefits
In a study by Eli Lilly called the SYNERGY patients who received either 5mg, 10mg or 15mg dose of tirzepatide showed no worsening of fatty liver disease parameters in 51.8%, 62.8% and 73.3% of study subjects respectively, after 52 weeks compared to only 13.2% of those who received a placebo
M., Best, K
Discussion This study adds to the limited available data on the use of semaglutide in patients with advanced CKD and provides insight over a prolonged follow-up period exceeding three years (median 1,187 days [IQR 6021,442]), with the majority of patients receiving maintenance hemodialysis (58.8%)
