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Hasta la fecha han sido identificadas ms de 50 enzimas que catalizan diversas modificaciones de histonas20,21, las cuales han sido clasificadas de acuerdo al tipo de reaccin que llevan a cabo

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This study found that JMF4073 treatment suppresses the in vitro and in vivo growth of WT-Bcr-Abl-transformed leukemia cells, but T315I-Bcr-Abl-transformed cells are less susceptible

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