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These lumps are not just cosmetic concerns
Injection Technique : Subcutaneous injection at a depth of 6-13mm
Notably, GLP-1RA use was also a marker of increased comorbidity, with a significantly higher Charlson comorbidity index in those using GLP-1RA in our tertiary center patient population
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VK2735 is a GLP-1/GIP dual agonist similar to tirzepatide (22.5% at 72 weeks), while retatrutide adds glucagon activation driving higher total weight loss
If their use is considered for a compelling comorbidity like obesity, caution is advised
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