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over time, it has been developed into a clinical drug for symptomatic therapy of AD (Heinrich and Lee, 2004

Supporting Study: LeRoith, D., et al

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2B demonstrate that the p-Akt protein expression levels were significantly decreased by TNF- treatment and then increased by 1000 ug/ml L-carnitine treatment, but 100 ug/ml L-carnitine showed no effect on p-Akt

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4.0 Future therapeutic opportunities in neurodegenerative diseases Recent clinical and preclinical evidence has established the potential of incretin mimetics to target pathological features central to neurodegenerative disorders