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In addition, IL-15, IL-17, IL-23, and GM-CSF have a strong relation to rheumatoid factor (RF), anti-cyclic citrullinated peptide (CCP) seropositivity, and RA activity, which could become diagnostic biomarkers for RA (64, 6769)
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Keep the vial in the main refrigerator compartment, not the door where temperature fluctuates
Are reconstituted peptides suitable for freezing
However, the largest Phase IIb trial involving 536 participants failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading to development termination in 2007
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