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Several factors contribute to the appearance: Subcutaneous fat loss is the primary cause
The Lancet 2014;384:134957
Beyond gastrointestinal effects, the following safety signals and class-relevant cautions warrant attention: Heart rate elevation: Retatrutide's glucagon receptor agonism has been associated with modest increases in resting heart rate in Phase 2 data
Xultophy is a combination of insulin and liraglutide and is used for treatment of type 2 diabetes
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