Decreased urine output or difficulty urinating, potentially signaling dehydration or kidney dysfunction Dark-colored or concentrated urine , which typically indicates dehydration, especially following gastrointestinal side effects Painful urination, urgency, or burning sensation , suggesting a possible urinary tract infection that may require antibiotics Blood in the urine (hematuria), which requires prompt evaluation regardless of other symptoms Foamy or frothy urine that persists, potentially indicating proteinuria or kidney disease Dehydration is a particular concern with semaglutide due to its gastrointestinal side effects
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Patients prescribed Wegovy should always inform their prescribing clinician about any supplements they are taking or considering
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Moreover, patients with NASH, particularly those with advanced metabolic risk factors like hypertension or type 2 diabetes, face a higher risk of adverse cardiovascular events and increased morbidity and mortality
It binds IGFBP-1, IGFBP-2, IGFBP-4, IGFBP-5, and IGFBP-6 with somewhat lower but still substantial affinity
