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Biochem Pharmacol 2002
If anemia and symptoms are severe, early labs (e.g
In a randomized placebo-controlled phase II trial in patients with metastatic colorectal cancer, calmangafodipir at a dose of 5 mol/kg reduced oxaliplatin-induced delay in the onset and intensity of CIPN symptoms during and after treatment and had no negative impact on progression free survival and overall survival outcomes [155]
doi: 10.1038/nrgastro.2015.200 93 OluboyedeOAEsanGJFrancisTILuzzattoL
The tissue lacks the robust blood supply that muscles enjoy, receives constant mechanical loading that disrupts healing, and often develops fibrotic scar tissue rather than healthy organized collagen
[PMID: 6149960] PubMed record related to this compound for laboratory literature review
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