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Animal infusion models do show blunting with continuous exposure, which is expected for any GPCR agonist

MPMS NPs, MPDMS NPs, and MPMSMPDMS hybrid NPs revealed that the abundance ratio of disulfide bonds to thiols increased with the increase in content rate of MPDMS in thiol-organosilica NPs

Spiering BA, Kraemer WJ, Vingren JL, Hatfield DL, Fragala MS, Ho J-Y, Maresh CM, Anderson JM, Volek JS

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Verhagen et al., 2019)

[PMID: 28042051] PubMed record related to this compound for laboratory literature review