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After control for confounding, the hazard ratio for self-harm was around the null value (1.03, 95% CI 0.70 to 1.51), and those for suicidal ideation and suicide were under the null value but with wide confidence intervals (0.84 (0.65 to 1.08) and (0.14 (0.02 to 1.31)), respectively (table 6)
19 Nevertheless, in 2017, the FDA added an warning to Januvia's package insert that advised prescribers to weigh the risks and benefits of sitagliptin in patients at risk for HF before initiating therapy
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