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So tirzepatide at 40C (104F) degrades about twice as fast as at 30C, and four times as fast as at 20C
however, oral semaglutide provides adequate systemic exposure over the body weight range of 40188 kg evaluated in clinical trials [4, 5, 8,9,10, 23]
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Additionally, as detected with a Seahorse XF analyzer, we found that the oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) were both decreased in ACTL6A-KD cells (Supplementary Fig 2d, e)
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