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doi:10.1097/00001622-200103000-00008
Additionally, GHK-Cu appears to regulate the TGF-/SMAD pathway a critical pathway involved in fibrosis (pathological scarring of organs)
It is therefore unsurprising that the LD 50 values for compounds 1 and 2 determined ex vivo have a similar discordance to that seen for PZQ when considering in vivo PK/PD: much like PZQ these compounds are schistosomicidal in vivo at sub LD 50 concentrations
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200 Disulphide-containing proteins have long been reported to be the major source of cystine in lysosomes via endoproteolysis
2015 Dec;102(6):1357-64
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