As mentioned, this unusual combining effect in hemostasis was recently evidenced with bleeding/thrombocytopenia after amputation, with or without anticoagulant and aspirin administration, abdominal aorta anastomotic site-thrombosis, both being counteracted [1,2]
In intact cells, activation of NFT yielded a radical anion, which subsequently initiated nuclear-factor-erythroid 2-related-factor-2 (Nrf2)-dependent induction of glutamate cysteine ligase (GCL)
Since TB-500 is not meant to be taken for periods longer than a few weeks to a few months for tissue repair, the role of angiogenesis in cancer growth need not be considered to be a red flag against the clinical use of this peptide
This pathway includes both forward and reverse
It is not a clinical recommendation
This creates shame and frustration, which deepens the depression further