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Anxiety and Depression: The unpredictable nature of the symptoms can lead to significant psychological distress, causing sufferers to avoid social situations and experience high levels of anxiety

Any changes to dosing should be discussed with the prescribing clinician

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Several observational studies and database analyses have examined whether people taking GLP-1 agonists experience changes in depressive symptoms compared to those on alternative treatments

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the 2024 AlphaWave stress RCT and the 2025 sleep meta-analysis