After one year, patients switching from Wegovy maintained about 82% of their prior weight loss, while patients switching from Zepbound maintained about 78%
Long-acting GLP-1 receptor agonists have little effect on gastric emptying due to the development of tolerance to GLP-1 effects mediated by changes in parasympathetic tone (Wettergren et al, 1998
Iodine intake matters for thyroid function but rarely needs supplementation if you eat a varied diet including seafood, dairy, and iodized salt
More importantly, Sema was shown to regulate myocardial energy metabolism based on the regulation of NR4a1 in pathological cardiac remodeling
Recent studies have also explored the ocular risks associated with GLP-1 therapies
Some insurers may provide coverage, but it often depends on the specific plan and patients BMI