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The paradigm shifted dramatically with the release of multi-society guidance in October 2024, endorsed by the ASA, American Gastroenterological Association, American Society for Metabolic and Bariatric Surgery, International Society of Perioperative Care of Patients with Obesity, and Society of American Gastrointestinal and Endoscopic Surgeons [10]
There are two types of GABA receptors: GABA-A and GABA-B GABA-A receptors are ionotropic Cl (chloride ion) channels allowing chloride to flow into a cell
Injection-site reactions (redness, swelling)
It should also include: A realistic weight loss goal Nutrition guidance Protein and hydration planning Side effect education Follow-up appointments Movement recommendations Long-term weight maintenance planning This approach helps patients think beyond short-term weight loss
If you have been weighing your choices between these two treatments, knowing the science behind each one, practical dosing details, and real-world outcomes will help you make a confident decision
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