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First, the mechanical agitation subjects peptide chains to shear forces at the liquid-air interface

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doi: 10.1096/fasebj.31.1_supplement.888.5 20 HellstrmPMSmithsonAStowellGGreeneSKennyEDamicoCet al

In the M-ARCOL model (Mucosal Artificial Colon, an advanced in vitro system using microbiota from healthy donors), daily exposure to PEMPs for 14 days increased pathobiont Desulfovibrionaceae (Fournier et al., 2023)

Bacopa also reduced levels of salivary cortisol (the primary stress hormone in the body) and had positive effects on mood in this trial, suggesting bacopa may work in part as an adaptogenan agent that increases stress resilience

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