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No treatment should be used if you or any family members have had medullary thyroid carcinoma (MTC), or if you have a condition known as Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

This dual mechanism is why tirzepatide consistently produces greater weight loss in clinical trials

Its important not to draw conclusions about how well Wegovy is working until you've been at your maintenance dose for a meaningful period

Similarly, Chee et al.[8] found that increasing skeletal muscle L-carnitine content by 20% in older adults enhanced whole-body fat oxidation by 20% during moderate-intensity exercise, primarily through greater intramyocellular lipid utilization

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Dehydration and acute kidney injury : Gastrointestinal side effects can lead to dehydration, particularly in the early weeks of treatment