In the recent past, BP has been associated with other drugs acting on the incretin pathway, namely dipeptidyl peptidase 4 (DPP4) inhibitors (especially linagliptin) [68,69,70,71]
The mechanism of weight gain is unclear but probably involves a combination of fluid retention and fat accumulation
Second, preclinical enthusiasm outpaces clinical confirmation
Nevertheless, observational studies such as these cannot determine whether low levels of vitamin B12 were the cause of the weight gain or whether higher levels of vitamin B12 protected against lower levels
Continuous access to clinical advice, even outside business hours, reduces the chance that a small appetite change becomes a larger setback
Your doctor will work with you to determine the appropriate duration based on your progress, tolerance to the medication, and weight loss goals