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While protocols vary, a typical dosage starts at 2mg once weekly and is increased at four-week intervals to reach a final dose of 10-15mg
and avoiding combination with other GLP-1 receptor agonists or DPP-4 inhibitors
Administered as a weekly injection, Tirzepatide has demonstrated impressive results in terms of weight reduction
Data on the CV benefits of GLP-1 RAs and their use in clinical practice were summarized
Current pricing levels (~USD 900/month) keep adoption in single digits, but every halving of net price can nearly double penetration, provided supply and prescriber infrastructure are stable
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