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[15] Patients should also seek immediate medical advice if they experience severe, persistent abdominal pain with or without vomiting (which could indicate pancreatitis), or right upper quadrant pain, fever, or jaundice (which could indicate gallbladder disease) both are important warnings in the FDA labeling for semaglutide products

Estimated treatment differences between cohorts showed the semaglutide 2.4 mg cohort had significantly greater percentage ( 15.0%) and absolute reduction in weight ( 15.7 kg), greater reduction in BMI ( 4.2 kg/m 2 ), and significantly greater improvements in cardiometabolic risk factors, including SBP ( 6.7 mmHg), DBP ( 2.7 mmHg), HbA1c ( 0.5%), HDL-C (1.2 mg/dl), LDL-C ( 10.4 mg/dl), and triglycerides ( 34.3 mg/dl) at 12 months

Clinicians recommend not continuing GLP-1 medication while severe dehydration or other acute medical issues are being treated, and advise follow-up before restarting therapy

Rekha Kumar, endocrinologist and associate professor of clinical medicine at Weill Cornell, told NBC's Anne Thompson during an Oct