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Studies in GHD patients receiving hGH therapy report [15]: Improved quality of life 2-5% increase in lean muscle mass 7-10% lower fat mass and a -1.2inch mean decrease in waist circumference 11-16% lower LDL (bad) cholesterol Yet, the benefits of hGH therapy in otherwise healthy individuals appear to be more modest

The purification of estrogen in the 1920s to the discovery of estrogen receptors defining estrogens affinity, binding, and the molecular mechanisms of gene activation in cells/tissues has been reviewed

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