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Also, GLP-1 is known to induce nitric oxide mediated vasodilation, and rodent studies have demonstrated that GLP-1 infusion acutely increases microvascular perfusion [15]

STEP 4 randomised people whod lost 10.6% on semaglutide to either continue the medication or switch to placebo

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The new phase 3 readout showed 20.8% in TRIUMPH-2 and 22.6% in TRIUMPH-3 at 80 weeks

### Step 4: Add Water to Peptide Slowly and at an Angle Insert the syringe needle through the retatrutide vial stopper at a 45-degree angle

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