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Weight loss through semaglutide also reduces mechanical stress on joints, improving mobility and quality of life in people with knee and hip arthritis

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Over time, however, the treatment effect of a marginal 30-week regimen dissipated

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In both trials, body mass index was required to be 20.029.9 kg/m 2

Over 36 months, the cumulative incidence of NAION was significantly higher in those prescribed semaglutide than those on a non-GLP-1 RA, with rates of 8.9% and 1.8%, respectively