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This pharmacokinetic profile provides a natural taper period, though patients should understand that appetite suppression and glycemic benefits will progressively decline during this window

Clinical evidence suggests that metabolic adaptations made during 1224 months of therapyimproved insulin sensitivity, reduced cravings, and restored satiety signalscan persist even after medication stops if lifestyle habits remain consistent

At the translational clinical level, L-carnitine primarily targets hepatic steatosisthe earliest pathological step in MASLD

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There will usually be a gradual diminution of the hyperpigmentation after the medication is discontinued [6]