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CHIVA is unique among venous disease treatments in that it preserves rather than destroys superficial veins, attempting to restore healthy blood flow by correcting venous hypertension (Bellmunt-Montoya 2015

Gupta et al

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Also nasal spray devices are typically 12.0 units per spray (125uL) The solution to get that into 4 sprays containing 20mg per spray (1 dose) = 80mg delivered would be a 16% concentration

Maintain Realistic Expectations Skin improvements take time

It can also occur with people who have bariatric surgery