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[13] Potential Risks and Side Effects of B12 Injections Whilst B12 injections are generally considered safe due to the vitamin's water-soluble nature (excess is excreted renally), several adverse effects and risks warrant consideration

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Hunt A, Harrington D, Robinson S

Follow-Up: Regular follow-up appointments to monitor your progress and adjust your treatment as necessary.

He then wrote a memorandum to physicians some of you may know it

However, you should: Call 999 or go to A&E immediately if you experience signs of a severe allergic reaction (difficulty breathing, severe throat/facial swelling, or collapse) Contact your GP if you experience a rash, itching, persistent pain at the injection site, or worsening neurological symptoms despite treatment If you suspect any side effects from your B12 injections, you can report them through the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk)