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The risk of renal adverse reactions was increased in patients with a history of renal impairment (the weight management trials included 65 patients with a history of moderate or severe renal impairment at baseline), and occurred more frequently during dose titration

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To reduce the risk of a positive test, athletes should follow the minimum washout periods recommended by WADA

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Hayes PC et al

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One experiment in rats found improved healing of a severed Achilles tendon [5]

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Interact with neurotransmitter systems , possibly affecting serotonin, dopamine, and GABA signaling pathways

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