When a medicine is used off-label (for example, if your doctor prescribes a diabetes medication like Ozempic for weight loss), insurance will most likely not cover it
People who are very sensitive to medications or who have a history of severe nausea may also benefit from spending more time at lower doses
These factors are reflected in the joint ADAEASD guidelines, which place a focus on putting the patient at the center of the treatment paradigm and consider that shared decision-making between patient and provider is essential to create an effective management plan [68]
Case reports and observational data suggest some patients with quiescent (inactive) ulcerative colitis have tolerated GLP-1 therapy without disease flares, while others have experienced symptom exacerbation
doi: 10.1136/bmj.h56 78 HankeyGJ
Above 2% there is no additional human evidence of benefit, and a higher copper load raises tolerability questions without established upside