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In a response to questions about Pfizer ending the trial of its oral drug, a company spokesperson pointed Scientific American to the press release that announced that decision and said Pfizer is working on other early-stage oral drug candidates for weight loss, including one that works on a similar hormone to GLP-1 that is currently in phase 2 clinical trials
The 2.5 mg beginning dose delivers therapeutic benefit while remaining below thresholds associated with severe nausea or appetite suppression that might interfere with nutrition during early treatment weeks
Jennifer Frediani, PhD, RD Medical Reviewer Jennifer K
Science 229 , 13581365 (1985)
You can find more about preventing these issues in peptide-storage-stability-guidelines-2
Moreover, GLP-1 therapies may improve endothelial function and vascular health
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