The October 2024 international consensus guidance, including from the American Society of Anesthesiologists, took a more nuanced position than earlier blanket-stop advice: 11 Patients on stable doses, without GI symptoms, who are not in the dose-escalation phase can usually continue their medication before elective surgery Higher-risk patients (recent dose escalation, GI symptoms, very high doses) should follow a 24-hour clear-liquid diet before standard 6-hour fasting For emergency surgery, the anaesthetist will use techniques that protect against aspiration regardless of fasting The specific plan should be agreed with your surgical team and anaesthetist in advance
The clinical benefit is real but indirect
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One of the biggest benefits of receiving B12 in this way is that it enables your natural levels of B12 to be boosted very quickly and you know exactly how much your body has received
This is why major medical organizations caution against viewing B12 shots as universal performance enhancers