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Glutathione depletion causes cytochrome c release even in the absence of cell commitment to apoptosis
However, if patients are taking warfarin, more frequent INR monitoring may be needed when starting or adjusting Wegovy doses, as advised in the SmPC
Currently, the only specific antidote for AILI remains NAC, but the benefit of NAC tends to decrease with the time passed between APAP challenge and treatment
As semaglutide degrades, it can form breakdown products that were not in the original formulation
Gorio A et al
Anand U, et al
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