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One analysis that showed benefit in type 2 diabetic patients suggests it may be more helpful in younger patients or with short-term treatment (14) , while another associated berberine with anthropometric improvements that may indirectly affect metabolic disease symptoms (15)

Neurosci Biobehav Rev 169:105995

Vitamin B12 is essential for red blood cell production and nerve function, while Folic Acid is crucial for DNA synthesis and preventing neural tube defects

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Interestingly, GLP-1RAs showed significantly more reduction in cardiovascular endpoints than metformin

Kim A, Krishnan A, Hamilton JP, Woreta TA (2021) The impact of dietary patterns and nutrition in nonalcoholic fatty liver disease